t Requirement of Endogenous Basic Fibroblast Growth Factor for Sensitization to Amphetamine

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Requirement of endogenous basic fibroblast growth factor for sensitization to amphetamine.

Repeated exposure to amphetamine produces long-lasting increases in sensitivity to its effects. We reported previously that repeated amphetamine treatment results in increased astrocytic expression of basic fibroblast growth factor (bFGF) in the ventral tegmental area (VTA) and substantia nigra compacta (SNc) and that this effect is prevented by coadministration of a nonspecific glutamate recep...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 2000

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.20-02-j0003.2000